![]() Although data regarding the benefits of testing women with PID for M. genitalium cervical infection prevents development of PID or endometritis. No clinical trial data are available that demonstrate that treating M. genitalium in establishing subsequent PID demonstrated increased PID risk however, these were not statistically significant associations, often because of a lack of statistical power. The few prospective studies that have evaluated the role of M. genitalium and PID, even those that controlled extensively for other infections and behavioral and biologic risk, are cross-sectional. genitalium in histologically defined endometritis have reported significantly elevated risk for PID ( 928). Recent studies evaluating the lower and upper genital tract using highly sensitive M. The association with PID is supported by early studies among nonhuman primates that determined that endosalpingitis develops after inoculation with M. genitalium among women with PID ranges from 4% to 22% ( 925, 926) and was reported as 60% in one study of women with postabortal PID ( 918). genitalium is identified in the cervix or endometrium of women with PID more often than in women without PID ( 918– 924). genitalium, with return to baseline levels after clearance of the pathogen ( 917). Elevated proinflammatory cytokines have been demonstrated among women with M. genitalium and cervicitis is mostly supportive of a causal association. genitalium can be detected among 10%–30% of women with clinical cervicitis ( 767, 770, 772, 914– 916). genitalium infections among women are also frequently asymptomatic, and the consequences associated with asymptomatic M. genitalium has been associated with cervicitis, PID, preterm delivery, spontaneous abortion, and infertility, with an approximately twofold increase in the risk for these outcomes among women infected with M. genitalium among men are unknown.Īmong women, M. The consequences of asymptomatic infection with M. genitalium infection with chronic complications among men (e.g., epididymitis, prostatitis, or infertility). ![]() trachomatis is common in selected geographic areas ( 911– 913), although M. genitalium causes symptomatic and asymptomatic urethritis among men and is the etiology of approximately 15%–20% of NGU, 20%–25% of nonchlamydial NGU, and 40% of persistent or recurrent urethritis ( 697, 909, 910). ![]()
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